Article

In silico biophysics and rheology of blood and red blood cells in Gaucher Disease

2024-12-12

Abstract excerpt

Gaucher Disease (GD) is a rare genetic disorder characterized by a deficiency in the enzyme glucocerebrosidase, leading to the accumulation of glucosylceramide in various cells, including red blood cells (RBCs). This accumulation results in altered biomechanical properties and rheological behavior of RBCs, which may play an important role in blood rheology and the development of bone infarcts, avascular necrosis (...

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Literature Corpus work: 3475b9c5-03ad-5cc3-bbb9-d91bd3219940
DOI: 10.1101/2024.12.10.627687

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