Article

The pattern of alternative splicing in lung adenocarcinoma shows novel events correlated with tumorigenesis and immune microenvironment

2021-11-04

Abstract excerpt

Lung adenocarcinoma (LUAD) is the leading cause of cancer deaths worldwide due to the lack of early diagnostic markers and specific drugs. Previous studies have shown the association of LUAD growth with aberrant alternative splicing (AS). Herein, clinical data of 535 tumor tissues and 59 normal tissues were extracted from the TCGA database. Each sample was analyzed using the ESTIMATE algorithm; a comparison betwee...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 343bfa83-e092-5f65-8b83-a824e9b54836
DOI: 10.21203/rs.3.rs-960327/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The pattern of alternative splicing in lung adenocarcinoma shows novel events correlated with tumorigenesis and immune microenvironmentDOI 10.21203/rs.3.rs-960327/v2Read

Development of alternative splicing signature in lung squamous cell carcinomaSemantic proximity Read

Identification of prognostic candidate signatures by systematically revealing transcriptome characteristics in lung adenocarcinoma with differing tumor microenvironment immune phenotypes.Semantic proximity Read

Global profiling of alternative splicing in non-small cell lung cancer reveals novel histological and population differencesSemantic proximity Read

Significance of Spliceosome‐Related Genes in the Prediction of Prognosis and Treatment Strategies for Lung AdenocarcinomaSemantic proximity Read

Systematic identification of cancer-related long noncoding RNAs and aberrant alternative splicing of quintuple-negative lung adenocarcinoma through RNA-Seq.Semantic proximity Read

A novel basement membrane-related gene signature for prognosis of lung adenocarcinomasSemantic proximity Read

Identification of tumour immune microenvironment-related alternative splicing events for the prognostication of pancreatic adenocarcinoma.Semantic proximity Read

Long non-coding RNA C5orf64 is a potential indicator for tumor microenvironment and mutation pattern remodeling in lung adenocarcinoma.Semantic proximity Read

Landscape and dynamics of single tumor and immune cells in early and advanced‐stage lung adenocarcinomaSemantic proximity Read

Survival-associated alternative splicing signatures in esophageal carcinomaSemantic proximity Read

Genome-Wide Profiling of Alternative Splicing Signature Reveals Prognostic Predictor for Esophageal CarcinomaSemantic proximity Read

Building a Risk Scoring Model for ARDS in Lung Adenocarcinoma Patients Using Machine Learning Algorithms.Semantic proximity Read