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Article

Long non-coding RNA C5orf64 is a potential indicator for tumor microenvironment and mutation pattern remodeling in lung adenocarcinoma.

Genomics - 1 Jan 2021

Pang Zhaofei, Chen Xiaowei, Wang Yu, Wang Yadong, Yan Tao, Wan Jun, Wang Kai, Du Jiajun

Abstract excerpt

Understanding the synergistic and antagonistic effects of tumor microenvironment (TME) and tumor mutation pattern on lung adenocarcinoma (LUAD) is urgently needed. Herein, we applied ESTIMATE and CIBERSORT methods to calculate the ratio of immune and stromal components and TIICs proportion of LUAD samples from TCGA database. Immune-related genes were analyzed by Lasso regression analysis and used for ceRNA...

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Adenocarcinoma of Lung
B7-H1 Antigen
Computational Biology
CTLA-4 Antigen
Programmed Cell Death 1 Receptor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Long Noncoding

Tumor Microenvironment

Tumor Suppressor Protein p53

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PMID: 33309768
DOI: 10.1016/j.ygeno.2020.12.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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