Article

SPIB Acts as a Tumor Suppressor by Activating NFkB and JNK Signaling Pathways Through MAP4K1 in Colorectal Cancer Cells

2020-12-31

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Colorectal cancer (CRC) is one of the major cancers in the world. Spi-B Transcription Factor (SPIB) is one member of the E-twenty-six (ETS) transcription factor family. Previous studies have shown that the expression of SPIB is down-regulated in human colorectal cancer tissues. However, its biological function in colorectal cancer cells is not reported. The purpos...

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Literature Corpus work: 34309324-1186-57f4-9e7a-7c96b8af807b
DOI: 10.21203/rs.3.rs-136420/v1

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