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SPAG5 Promotes the Proliferation, Migration, Invasion, and Epithelial-Mesenchymal Transformation of Colorectal Cancer Cells by Activating the PI3K/AKT Signaling Pathway

2 Aug 2023

Abstract excerpt

Colorectal cancer (CRC) is a cancer that occurs in the rectum or colon with a high incidence. Sperm-associated antigen 5 (SPAG5), a gene that regulates cell division, has been observed highly expressed in a variety of cancers, but its role in CRC is unclear. This study aimed to investigate the regulatory role of SPAG5 in CRC. The expression of SPAG5 in multiple cancers and normal tissues was predicted by The...

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PMID: 37929348
DOI: 10.4103/cjop.cjop-d-22-00165

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