Article

Growth Hormone Activates PI3K/Akt Signaling and Inhibits ROS Accumulation and Apoptosis in Granulosa Cells of Patients With Polycystic Ovary Syndrome

2020-09-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Growth hormone (GH) can reduce oxidative stress (OS) induced apoptosis in some types of cells by activating the PI3K/Akt signaling pathway. This study investigated the role and underlying mechanism of GH in OS and apoptosis in GCs of patients with polycystic ovary syndrome (PCOS). <bold>Methods: </bold>Primary GCs were collected from patients with and without PC...

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Literature Corpus work: 33c3d6a3-8ebd-52f6-8950-ef49abf967c3
DOI: 10.21203/rs.3.rs-76999/v1

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