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Article

Upregulation of PD-L1 contributes to improving the apoptosis of granulosa cells via the PI3K/AKT pathway in PCOS

11 Dec 2024

Abstract excerpt

PURPOSE: Polycystic ovary syndrome (PCOS) is a leading cause of anovulatory infertility and closely correlated with apoptosis in ovarian granulosa cells (GCs). Programmed cell death protein-1/programmed cell death ligand-1 (PD-1/PD-L1) pathway plays an important role throughout gestation and the pathogenesis of adverse pregnancy outcomes, but its mechanism in PCOS remains unclear. METHODS: The RNA sequencing data...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39663282
DOI: 10.1007/s10815-024-03327-y

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