Article

A highly expressing, soluble, and stable plant-made IgG fusion vaccine strategy enhances antigen immunogenicity in mice without adjuvant

2020-07-14

Abstract excerpt

<h4>Summary</h4> Therapeutics based on fusing a protein of interest to the IgG Fc domain have been enormously successful, though fewer studies have investigated the vaccine potential of IgG fusions. In this study, we systematically compared the key properties of seven different plant-made human IgG1 fusion vaccine candidates using Zika virus (ZIKV) envelope domain III (ZE3) as a model antigen. Complement protein...

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Literature Corpus work: 33b30e6a-2a73-5a23-9f04-89bfb44e428a
DOI: 10.1101/2020.07.13.199703

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