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Development and qualification of an enzyme-linked immunosorbent assay to detect human serum immunoglobulin G reactive to multiple lineages of Lassa virus nucleoprotein

2025-12-26

Abstract excerpt

Lassa fever is a severe, often fatal febrile illness endemic to West Africa caused by Lassa virus (LASV). The viral nucleoprotein (NP) is a target antigen for serological assays to identify previous exposure to LASV. To our knowledge, there is no commercially available assay that reliably quantifies anti-LASV-NP IgG antibodies in human serum. We report the development and qualification of an ELISA designed to dete...

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Literature Corpus work
33631f11-fa6c-5442-abfc-dd4cdb0aaa4f
DOI
10.64898/2025.12.25.696537
Open publication

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Development and qualification of an enzyme-linked immunosorbent assay to detect human serum immunoglobulin G reactive to multiple lineages of Lassa virus nucleoproteinDOI 10.64898/2025.12.25.696537
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