Rodent control of chamber brightness leads to the emergence of unique circadian rhythms

Abstract excerpt

Internal circadian rhythms deviate slightly from 24 h, depending on species and individuals; thus, an environment with a 24-h light/dark cycle may not be ideal. In this study, we enabled mice to control room brightness via nose pokes and investigated subsequent biological rhythms as well as physiological and cognitive functions. The mice immediately learned the relationship between nose pokes and the resulting ill...

Topics

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• Basic Helix-Loop-Helix Transcription Factors
• Circadian Rhythm
• CLOCK Proteins
• Gene Knockout Techniques
• Locomotion
• Mice
• Phenotype
• Suprachiasmatic Nucleus

Identifiers and source

Literature Corpus work

3311610e-df00-589b-afc6-43b4ecf72b8b

DOI

10.21203/rs.3.rs-2790368/v1