Article

SARS-CoV-2 Innate Effector Associations and Viral Load in Early Nasopharyngeal Infection

2020-11-04

Abstract excerpt

To examine innate immune responses in early SARS-CoV-2 infection that may change clinical outcomes, we compared nasopharyngeal swab data from 20 virus-positive and 20 virus-negative individuals. Multiple innate immune-related and ACE-2 transcripts increased with infection and were strongly associated with increasing viral load. We found widespread discrepancies between transcription and translation. Interferon pro...

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Literature Corpus work: 32bd0f1f-ddca-51d6-8a4b-83e01b78c04b
DOI: 10.1101/2020.10.30.20223545

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