Article

P2X7 Receptor Antagonist Attenuates Retinal Inflammation and Neovascularization Induced by Oxidized Low Density Lipoprotein

2020-07-06

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Inflammation and neovascularization are two vital pathological phases of AMD. Recent evidence indicates that blocking P2X7 receptor may relieve inflammation. Here, we investigated whether A740003, a P2X7 receptor antagonist, could prevent retinal inflammation and neovascularization induced by ox-LDL and explored the underlying mechanisms.<bold>Methods: </bold>AR...

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Literature Corpus work: 327452de-5e71-5c1b-b7c2-05a28a018111
DOI: 10.21203/rs.3.rs-39937/v1

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