Article

The α2A-adrenergic receptor on Tfh cells amplifies allergic airway inflammation via Akt signaling

2025-11-14

Abstract excerpt

<title>Abstract</title> <p> Bronchial asthma is a prevalent chronic inflammatory disease characterized by aberrant immune regulation. While β2-adrenergic signaling has been extensively studied in asthma, the role of other adrenergic receptors remains unclear. Here, we identify α2A-adrenergic receptor (α2AR, coded by <italic>Adra2a</italic> ) as a key modulator of allergic airway inflammation. Transcriptomic an...

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Literature Corpus work: 322be50a-216d-5d96-a7d8-9d102fb3af5b
DOI: 10.21203/rs.3.rs-7932656/v1

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