Article
A Neurogenic Signature Involving Monoamine Oxidase-A controls Human Thermogenic Adipose Tissue Development
2021-12-30
Abstract excerpt
<h4>ABSTRACT</h4> Mechanisms that control “beige/brite” thermogenic adipose tissue development may be harnessed to improve human metabolic health. To define these mechanisms, we developed a species-hybrid model in which human mesenchymal progenitor cells were used to develop white or thermogenic/beige adipose tissue in mice. The hybrid adipose tissue developed distinctive features of human adipose tissue, such as...
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Identifiers and source
- Literature Corpus work
- 32063592-48be-5415-b92f-1d3c4d1758a8
- DOI
- 10.1101/2021.12.29.474474