Article

Two mutations in the SARS-CoV-2 spike protein and RNA polymerase complex are associated with COVID-19 mortality risk

2020-11-24

Abstract excerpt

<h4>Background</h4> SARS-CoV-2 mortality has been extensively studied in relation to host susceptibility. How sequence variations in the SARS-CoV-2 genome affect pathogenicity is poorly understood. Whole-genome sequencing (WGS) of the virus with death in SARS-CoV-2 patients is one potential method of early identification of highly pathogenic strains to target for containment. <h4>Methods</h4> We analyzed 7,548 s...

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Literature Corpus work: 31b6a7cb-6f51-5347-9cbd-bdd8c7f996f3
DOI: 10.1101/2020.11.17.386714

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