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Article

The longer transmembrane helices of class I viral fusion proteins may facilitate viral fusion

2025-09-25

Abstract excerpt

The viral envelope-resident viral fusion proteins (VFPs) fuse the envelope with the host cell membrane, which allows virus entry into host cells. The homotrimeric class I VFPs (cI-VFPs) are anchored to the envelope by three single-pass transmembrane helices (spTMHs). It is generally accepted that the hydrophobic length of a TMH matches the thickness of the hydrophobic membrane core, and this reduces TMH dynamics b...

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Identifiers and source

Literature Corpus work
31a19999-0b09-575b-8a04-af1e096fda59
DOI
10.1101/2025.09.25.678357
Open publication

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The longer transmembrane helices of class I viral fusion proteins may facilitate viral fusionDOI 10.1101/2025.09.25.678357
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