Article

Optimizing Cardiovascular Treatment in Non-Small Cell Lung Cancer: A Comprehensive Computational Approach for Assessment of Drug-Drug Interactions between Tyrosine Kinase Inhibitors and Cardiovascular Drugs

2025-03-19

Abstract excerpt

<h4>Background: </h4> As lung cancer treatment has progressed, there has been an increase in awareness of the short- and long-term adverse effects of targeted cancer therapies of tyrosine kinase inhibitors, particularly cardiovascular toxicities. Methods The current study assessed the potential drug interactions using interaction drug-interaction checkers (IBM Micromedex and Drugs.com). Molecular docking was emplo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3067b234-19c3-5450-9186-371d821e2355
DOI: 10.12688/f1000research.162353.1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Optimizing Cardiovascular Treatment in Non-Small Cell Lung Cancer: A Comprehensive Computational Approach for Assessment of Drug-Drug Interactions between Tyrosine Kinase Inhibitors and Cardiovascular DrugsDOI 10.12688/f1000research.162353.1Read

Optimizing Cardiovascular Treatment in Non-Small Cell Lung Cancer: A Comprehensive Computational Approach for Assessment of Drug-Drug Interactions Between Tyrosine Kinase Inhibitors and Cardiovascular DrugsSemantic proximity Read

Cardiotoxicity Associated with Targeted Therapies in Lung Cancer: A Retrospective Cohort Study of 2,427 Patients with FAERS Pharmacovigilance ValidationSemantic proximity Read

Computational platform for modelling, analysis, and prediction of anti-EGFR drug resistance for lung cancer.Semantic proximity Read

Computational study of novel natural inhibitors targeting Kirsten rat sarcoma viral oncogene homolog G12C.Semantic proximity Read

In silico Multi-Target Pharmacological Profiling of Itraconazole: Molecular Docking, Binding Free Energy Estimation, and Systems Biology Insights into Potential Anti-Cancer MechanismsSemantic proximity Read

A brief survey on computational approaches to reveal drug and disease associations.Semantic proximity Read

Identification and molecular modelling of potential drugs targeting the genes involved in the progression of lung cancer in patients with idiopathic pulmonary fibrosisSemantic proximity Read

[A review: drug-drug interactions of epithelial growth factor receptor-tyrosine kinase inhibitors].Semantic proximity Read

Computational Methods for the Analysis and Prediction of EGFR-Mutated Lung Cancer Drug Resistance: Recent Advances in Drug Design, Challenges and Future Prospects.Semantic proximity Read

Genomic and computational-aided integrative drug repositioning strategy for EGFR and ROS1 mutated NSCLC.Semantic proximity Read

Drug repurposing for COVID-19 using computational screening: Is Fostamatinib/R406 a potential candidate?Semantic proximity Read

Research Progress on the Cardiotoxicity of EGFR-TKIs in Non-Small Cell Lung Cancer.Semantic proximity Read