Article
Genomic and computational-aided integrative drug repositioning strategy for EGFR and ROS1 mutated NSCLC.
International immunopharmacology - 30 Sept 2024
Tripathi Varsha, Khare Aishwarya, Shukla Divyanshi, Bharadwaj Shiv, Kirtipal Nikhil, Ranjan Vandana
Abstract excerpt
Non-small cell lung cancer (NSCLC) has been marked as the major cause of death in lung cancer patients. Due to tumor heterogeneity, mutation burden, and emerging resistance against the available therapies in NSCLC, it has been posing potential challenges in the therapy development. Hence, identification of cancer-driving mutations and their effective inhibition have been advocated as a potential approach in NSCLC...
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