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Murine monoclonal antibodies against RBD of SARS-CoV-2 neutralize authentic wild type SARS-CoV-2 as well as B.1.1.7 and B.1.351 viruses and protect <i>in vivo</i> in a mouse model in a neutralization dependent manner

2021-04-06

Abstract excerpt

After first emerging in December 2019 in China, severe acute respiratory syndrome 2 (SARS-CoV-2) has since caused a pandemic leading to millions of infections and deaths worldwide. Vaccines have been developed and authorized but supply of these vaccines is currently limited. With new variants of the virus now emerging and spreading globally, it is essential to develop therapeutics that are broadly protective and b...

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Literature Corpus work
2ff800f7-11a6-5bbc-8eac-518d4b6efff3
DOI
10.1101/2021.04.05.438547
Open publication

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Murine monoclonal antibodies against RBD of SARS-CoV-2 neutralize authentic wild type SARS-CoV-2 as well as B.1.1.7 and B.1.351 viruses and protect <i>in vivo</i> in a mouse model in a neutralization dependent mannerDOI 10.1101/2021.04.05.438547
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