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The Evolution of Triple-Negative Breast Cancer: From Biology to Novel Therapeutics.

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting - 1 Jan 2016

Anders Carey K, Abramson Vandana, Tan Tira, Dent Rebecca

Abstract excerpt

Triple-negative breast cancer (TNBC) is clinically defined as lacking expression of the estrogen receptor (ER), progesterone receptor (ER), and HER2. Historically, TNBC has been characterized by an aggressive natural history and worse disease-specific outcomes compared with other breast cancer subtypes. The advent of next-generation sequencing (NGS) has allowed for the dissection of TNBC into molecular subtypes...

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Molecular Targeted Therapy
Neoadjuvant Therapy
Phosphatidylinositol 3-Kinases
Receptor, ErbB-2
Receptors, Estrogen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Progesterone

Triple Negative Breast Neoplasms

Tumor Suppressor Protein p53

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PMID: 27249684
DOI: 10.1200/EDBK_159135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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