Article

Genotype-Specific HPV mRNA Triage Enhances CIN2+ Detection Efficiency Compared to Cytology in HPV DNA-Positive Women

2025-07-01

Abstract excerpt

<h4>Background: </h4> Effective triage of women testing positive for high-risk HPV DNA is essential to reduce unnecessary colposcopies while preserving cancer prevention. Cytology, the current standard, has limited specificity and reproducibility. The genotype-specific 7-type HPV E6/E7 mRNA test (PreTect HPV-Proofer`7), targeting HPV types 16, 18, 31, 33, 45, 52, and 58, detects transcriptionally active infections...

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Literature Corpus work: 2fd5c46e-f7b8-5034-bbd4-9b5e62ec3eb4
DOI: 10.20944/preprints202506.2527.v1

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