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Genotype-Specific HPV mRNA Triage Improves Colposcopy Efficiency Compared with Cytology and ATHENA-Derived Triage: A Population-Based Study of HPV DNA-Positive Women.

Pathogens (Basel, Switzerland) - 28 May 2026

Sørbye Sveinung Wergeland, Falang Bente Marie, Antonsen Mona, Richardsen Elin

Abstract excerpt

BACKGROUND: Effective triage of HPV DNA-positive women is needed to reduce unnecessary colposcopies while maintaining cervical cancer prevention. We evaluated genotype-specific 7-type HPV E6/E7 mRNA triage in a real-world screening cohort. METHODS: In this population-based single-centre study at the University Hospital of North Norway, 42,791 women underwent primary screening with the cobas HPV DNA assay during...

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Identifiers

PMID: 42347196
DOI: 10.3390/pathogens15060584
PMCID: PMC13304981

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