Article

Blood gene expression-based prediction of lethality after respiratory infection by influenza A virus in mice

2020-10-27

Abstract excerpt

Lethality after respiratory infection with influenza A virus (IAV) is associated with potent immune activation and lung tissue damage. In a well-controlled animal model of infection, we sought to determine if one could predict lethality using transcriptional information obtained from whole blood early after influenza virus exposure. We started with publicly available transcriptomic data from the lung, which is the...

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Literature Corpus work: 2fbf5935-a0e5-5ca2-a5a0-dcbd476f6020
DOI: 10.1101/2020.10.27.357053

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