Article

Evidence for a role of human blood-borne factors in mediating age-associated changes in molecular circadian rhythms

2023-04-24

Abstract excerpt

<h4>ABSTRACT</h4> Aging is associated with a number of physiologic changes including perturbed circadian rhythms; however, mechanisms by which rhythms are altered remain unknown. To test the idea that circulating factors mediate age-dependent changes in peripheral rhythms, we compared the ability of human serum from young and old individuals to synchronize circadian rhythms in culture. We collected blood from app...

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Literature Corpus work: 2f97d091-fe5c-5009-8c66-33adbfc49eca
DOI: 10.1101/2023.04.19.537477

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