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Reconstruction of lncRNA-miRNA-mRNA network based on competitive endogenous RNA reveals functional lncRNAs in melanoma

2020-05-12

Abstract excerpt

<h4>Background: </h4> Melanoma is the most common and dangerous skin tumor, and its pathogenesis is not fully understood. <h4>Methods:</h4> To identify the key lncRNAs in melanoma, we reconstructed a global triple network based on the ceRNA theory. GO and KEGG pathway analysis were performed using DAVID. And, we verified our findings through qRT-PCR assay. <h4>Results:</h4> According to ceRNA theory, 898 DEMs,53 D...

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Literature Corpus work
2f116522-b125-535a-ad42-78c95178ef3d
DOI
10.21203/rs.2.23245/v2
Open publication

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Reconstruction of lncRNA-miRNA-mRNA network based on competitive endogenous RNA reveals functional lncRNAs in melanomaDOI 10.21203/rs.2.23245/v2
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