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Function and Clinical Implications of Long Non-Coding RNAs in Melanoma

28 Mar 2017

Abstract excerpt

Metastatic melanoma is the most deadly type of skin cancer. Despite the success of immunotherapy and targeted agents, the majority of patients experience disease recurrence upon treatment and die due to their disease. Long non-coding RNAs (lncRNAs) are a new subclass of non-protein coding RNAs involved in (epigenetic) regulation of cell growth, invasion, and other important cellular functions. Consequently,...

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PMID: 28350340
DOI: 10.3390/ijms18040715

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