Article

Adverse effects of antipsychotic drugs on metabolism depend on drug dosing and feeding times

2022-02-24

Abstract excerpt

Antipsychotic drugs (AP) are highly efficacious treatments for psychiatric disorders but are associated with significant metabolic side effects. The circadian clock maintains metabolic homeostasis by sustaining daily rhythms in feeding, fasting and hormone regulation but how circadian rhythms interact with AP and its associated metabolic side effects is not well known. In these studies, we investigated the impact...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2e59b8b1-2db3-5da4-b960-0be7dee8a820
DOI: 10.1101/2022.02.23.22271365

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Adverse effects of antipsychotic drugs on metabolism depend on drug dosing and feeding timesDOI 10.1101/2022.02.23.22271365Read

Metabolic side effects of antipsychotic drug treatment--pharmacological mechanisms.Semantic proximity Read

Long-Term Effects of Early Adolescent Second-Generation Antipsychotic Exposure on Body Weight, Caloric Intake, and Metabolism-Associated Gene ExpressionSemantic proximity Read

Clinical pharmacokinetics of antipsychotics in pediatric populations: a scoping review focusing on dosing regimen.Semantic proximity Read

Dosing Time MattersSemantic proximity Read

Legacy neuropsychiatric benefit after semaglutide is linked to maximum achieved dose and independent of the maximum weight lostSemantic proximity Read

Weight Gain and Metabolic Changes During Treatment with Antipsychotics and Antidepressants.Semantic proximity Read

Does Sex affect Antipsychotic Associated Weight Gain in Patients Being Treated for Psychotic Disorders: A Protocol for a Systematic ReviewSemantic proximity Read

GLP-1 Receptor Agonists at the Crossroads of Circadian Biology, Sleep, and Metabolic DiseaseSemantic proximity Read

Behavioral circadian phenotypes are associated with the risk of elevated body mass index.Semantic proximity Read

Examining side effect variation in antipsychotic treatment and schizophrenia spectrum disordersSemantic proximity Read

Antipsychotic medications and extreme weight gain in two health systems.Semantic proximity Read

Drawbacks of Olanzapine Therapy: An Emphasis on Its Metabolic Effects and DiscontinuationSemantic proximity Read