Article

Next generation sequencing of RB1gene for the molecular diagnosis of ethnic minority with retinoblastoma in Yunnan

2020-02-21

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Retinoblastoma is a rare intraocular malignancy and typically initiated by inactivating biallelic mutations of <italic>RB1</italic> gene. Each year, ~8,000 children worldwide are diagnosed for retinoblastoma. In high-income countries, patient survival is over 95% while low-income countries is ~30%.If disease is diagnosed early and treated in centers specializing...

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Literature Corpus work: 2e512d0e-891c-57b3-ab2a-4997bdf48e1e
DOI: 10.21203/rs.2.24190/v1

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