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Single-Cell and Spatial Transcriptomics Integration Identifies Mural Cell Oxidative Stress Genes <i>Clu</i> and <i>Gria2</i> as Key Biomarkers in Ischemic Stroke

2026-02-10

Abstract excerpt

<h4>ABSTRACT</h4> Oxidative stress (OS) is a key factor in ischemic stroke (IS), but the characterization of OS-related genes in IS remains largely unexplored. Identifying key OS-associated genes could improve our understanding of OS in IS. We analysed single-cell RNA sequencing datasets and utilized AUCell, Ucell, singscore, ssgsea, and AddModuleScore algorithms, along with correlation analysis, identified 167 O...

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Literature Corpus work
2dd02526-3c46-5447-8813-ce26a68f9e21
DOI
10.64898/2026.02.09.704987
Open publication

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Single-Cell and Spatial Transcriptomics Integration Identifies Mural Cell Oxidative Stress Genes <i>Clu</i> and <i>Gria2</i> as Key Biomarkers in Ischemic StrokeDOI 10.64898/2026.02.09.704987
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