Article

Identification of Cross-Reactive CD8 <sup>+</sup> T Cell Receptors with High Functional Avidity to a SARS-CoV-2 Immunodominant Epitope and Its Natural Mutant Variants

2020-11-03

Abstract excerpt

<h4>ABSTRACT</h4> Despite the growing knowledge of T cell responses and their epitopes in COVID-19 patients, there is a lack of detailed characterizations for T cell-antigen interactions and T cell functions. Using a peptide library predicted with HLA class I-restriction, specific CD8 + T cell responses were identified in over 75% of COVID-19 convalescent patients. Among the 15 SARS-CoV-2 epitopes identified fro...

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Literature Corpus work: 2d86fdec-a471-554a-890e-5f57b773382b
DOI: 10.1101/2020.11.02.364729

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