Explorative Discovery of Gene Signatures and Clinotypes in Glioblastoma Cancer Through GeneTerrain Knowledge Map Representation

Abstract excerpt

This study introduces the GeneTerrain Knowledge Map Representation (GTKM), a novel method for visualizing gene expression data in cancer research. GTKM leverages protein-protein interactions to graphically display differentially expressed genes (DEGs) on a 2-dimensional contour plot, offering a more nuanced understanding of gene interactions and expression patterns compared to traditional heatmap methods. The rese...

Topics

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• Bioinformatics and Genomic Networks
• Brain Neoplasms
• Computer Graphics
• Data Mining
• Databases, Genetic
• Datasets as Topic
• Glioma
• User-Computer Interface

Identifiers and source

Literature Corpus work

2cf1aa52-6b7c-52b4-8ab4-a8dffe9883ee

DOI

10.1101/2024.04.01.587278