Article

Transcription factors associated with regulation of transcriptome in human thigh and calf muscles at baseline and after six days of disuse

2024-12-15

Abstract excerpt

Disuse has a negative impact on the postural muscles of the trunk and legs. Different leg muscles demonstrate a differentiated and conservative response to disuse, in terms of a decrease in muscle mass, strength, aerobic performance, and changes in gene expression. We aimed to identify transcription factors regulating gene expression at baseline and after disuse in human m. soleus – a “slow” muscle with a strong...

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Literature Corpus work: 2ce098e9-518e-558e-9d9b-bd4523d3a56a
DOI: 10.1101/2024.12.10.627667

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