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Article

MEF2 as upstream regulator of the transcriptome signature in human skeletal muscle during unloading

11 Jul 2018

Abstract excerpt

Our understanding of skeletal muscle structural and functional alterations during unloading has increased in recent decades, yet the molecular mechanisms underpinning these changes have only started to be unraveled. The purpose of the current investigation was to assess changes in skeletal muscle gene expression after 21 days of bed rest, with a particular focus on predicting upstream regulators of muscle disuse....

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PMID: 29995456
DOI: 10.1152/ajpregu.00452.2017

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