Article

Disruption of Myelin-Associated Glycoprotein Activity Drives Aberrant Cerebellar Neurodevelopment and Autism-Like Behaviors

2026-06-13

Abstract excerpt

Immune-mediated mechanisms have emerged as important contributors to neurodevelopmental vulnerability in a subset of autism spectrum disorder (ASD) cases. Circulating IgG antibodies against myelin-associated glycoprotein (MAG) have been reported in individuals with ASD and their mothers; however, the pathogenic relevance of these antibodies and the contribution of MAG signaling to neurodevelopment remain unclear....

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Literature Corpus work: 2c76efe0-73f4-5d88-8e08-6b46c769a2ce
DOI: 10.64898/2026.06.11.731430

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