Article

Loss of coactosin-like F-actin binding protein 1 (Cotl1) decreases platelet-mediated osteoclastogenesis and causes osteopetrosis phenotypes in mouse

2023-12-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUNDS</h4> Osteopetrosis, a rare skeletal disease, is characterized by an increased bone mass resulting from impaired bone remodeling process. Platelet is the major bone-healing blood component involved in the regulation of bone resorption, particularly in the removal of compromised bones. Several actin-associated proteins contribute to the orchestration of actin ring formation in osteo...

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Literature Corpus work: 2c54cf74-c8eb-5696-beff-9b360e00d58e
DOI: 10.1101/2023.12.20.23300337

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Loss of coactosin-like F-actin binding protein 1 (Cotl1) decreases platelet-mediated osteoclastogenesis and causes osteopetrosis phenotypes in mouseDOI 10.1101/2023.12.20.23300337Read

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