Article
A spinal cord injury time and severity consensus transcriptomic reference suite in rat reveals translationally-relevant biomarker genes
2024-01-30
Abstract excerpt
Spinal cord injury (SCI) is a devastating condition that leads to motor, sensory, and autonomic dysfunction. Current therapeutic options remain limited, emphasizing the need for a comprehensive understanding of the underlying SCI-associated molecular mechanisms. This study characterized distinct SCI phases and severities at the gene and functional levels, focusing on biomarker gene identification. Our approach inv...
Topics
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- MicroRNA in disease regulation
- Neurogenesis and neuroplasticity mechanisms
- Neurogenetic and Muscular Disorders Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Neuroscience of respiration and sleep
- Osteoarthritis Treatment and Mechanisms
- Spinal Cord Injury Research
- Zebrafish Biomedical Research Applications
Identifiers and source
- Literature Corpus work
- 2c2c81ec-36b3-5148-98fb-6251445a81a6
- DOI
- 10.1101/2024.01.30.578030
