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A comprehensive transcriptional reference for severity and progression in spinal cord injury reveals novel translational biomarker genes

4 Feb 2025

Abstract excerpt

Spinal cord injury (SCI) is a devastating condition that leads to motor, sensory, and autonomic dysfunction. Current therapeutic options remain limited, emphasizing the need for a comprehensive understanding of the underlying SCI-associated molecular mechanisms. This study characterized distinct SCI phases and severities at the gene and functional levels, focusing on biomarker gene identification. Our approach...

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PMID: 39905473
DOI: 10.1186/s12967-024-06009-6

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