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Integrated systems analysis reveals conserved gene networks underlying response to spinal cord injury

1 Oct 2018

Abstract excerpt

Spinal cord injury (SCI) is a devastating neurological condition for which there are currently no effective treatment options to restore function. A major obstacle to the development of new therapies is our fragmentary understanding of the coordinated pathophysiological processes triggered by damage to the human spinal cord. Here, we describe a systems biology approach to integrate decades of small-scale...

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PMID: 30277459
DOI: 10.7554/elife.39188

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