Article

Detection of pyrophosphate and alkaline phosphatase activity based on PolyT single stranded DNA - copper nanoclusters

2022-03-31

Abstract excerpt

The determination of pyrophosphate and alkaline phosphatase activity plays a significant role in medical diagnosis. In this work, a label-free "ON-OFF-ON" fluorescence strategy is developed for the analysis of pyrophosphate and alkaline phosphatase activity. Using PolyT single strand DNA as templates to synthesize fluorescent copper nanoparticles, the coordination effect of pyrophosphoric acid on Cu 2+ inhibited t...

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Literature Corpus work: 2bfa4654-24b6-59c8-a3ae-7bf4a6f4cc46
DOI: 10.21203/rs.3.rs-1480822/v1

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