Article

Site-dependent transcriptomic signatures of endometriosis are conserved across hormonal states

2026-07-16

Abstract excerpt

Endometriosis, a chronic condition in which endometrial tissue grows at other sites in the body, produces lesions whose gene expression profiles vary by anatomical location and menstrual cycle stage. The extent to which these location-dependent transcriptional differences persist across hormonal states has remained unknown. Here, we compile a comprehensive single-cell RNA sequencing atlas of 672,051 cells across 1...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2be719c2-32dd-5ca6-84e5-515d37322520
DOI: 10.64898/2026.07.10.737856

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Site-dependent transcriptomic signatures of endometriosis are conserved across hormonal statesDOI 10.64898/2026.07.10.737856Read

An integrated single-cell reference atlas of the human endometriumSemantic proximity Read

An integrated single-cell reference atlas of the human endometriumSemantic proximity Read

Single-Cell Profiling Reveals Altered Endometrial Cellular Features Across the Menstrual Cycle in Endometriosis PatientsSemantic proximity Read

A cellular and molecular portrait of endometriosis subtypesSemantic proximity Read

An integrated multimodal pan-organ atlas of the female reproductive system across the lifespan contextualises gynaecological pathologiesSemantic proximity Read

Cellular heterogeneity and dynamics of the human uterus in healthy premenopausal womenSemantic proximity Read

Single‐cell transcriptomic atlas of different endometriosis indicating that an interaction between endometriosis‐associated mesothelial cells (EAMCs) and ectopic stromal cells may influence progesterone resistanceSemantic proximity Read

Single cell analysis of endometriosis reveals a coordinated transcriptional program driving immunotolerance and angiogenesis across eutopic and ectopic tissuesSemantic proximity Read

Tracing Endometriosis: Coupling deeply phenotyped, single-cell based Endometrial Differences and AI for disease pathology and predictionSemantic proximity Read

Endometriosis as a Systemic and Complex Disease: Toward Phenotype-Based Classification and Personalized Therapy.Semantic proximity Read

Cellular atlas of the human ovary using morphologically guided spatial transcriptomics and single-cell sequencingSemantic proximity Read

Single cell analysis of endometriosis reveals a coordinated transcriptional program driving immunotolerance and angiogenesis across eutopic and ectopic tissues.Semantic proximity Read