Article

The Disruption of SARS-CoV-2 RBD/ACE-2 Complex by Ubrogepant Is Mediated by Interface Hydration

2020-03-31

Abstract excerpt

<h4>Background: </h4> COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global pandemic affecting approximately 490,000 people and accounting for more than 22,000 deaths and has no generally cure. Here, the recently resolved 3D structure of SARS-CoV-2 receptor binding domain (RBD) in complex with its receptor-the angiotensin converting enzyme-2 (ACE-2) have provided the basis for...

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Literature Corpus work: 2bd98c5e-7939-5c27-86df-9ef7cc291232
DOI: 10.20944/preprints202003.0466.v1

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