Article

Evaluation of ComBat harmonization for reducing across-tracer differences in regional amyloid PET analyses

2024-06-15

Abstract excerpt

<h4>Introduction: </h4> Differences in amyloid positron emission tomography (PET) radiotracer pharmacokinetics and binding properties lead to discrepancies in amyloid-β uptake estimates. Harmonization of tracer-specific biases is crucial for optimal performance of downstream tasks. Here, we investigated the efficacy of ComBat, a data-driven harmonization model, for reducing tracer-specific biases in regional amylo...

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Literature Corpus work: 2bcaf381-4693-5e82-bdb7-3ae9fb9ba8b6
DOI: 10.1101/2024.06.14.24308952

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