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Impact of feature harmonization on radiogenomics analysis: Prediction of EGFR and KRAS mutations from non-small cell lung cancer PET/CT images.

Computers in biology and medicine - 1 Mar 2022

Shiri Isaac, Amini Mehdi, Nazari Mostafa, Hajianfar Ghasem, Haddadi Avval Atlas, Abdollahi Hamid, Oveisi Mehrdad, Arabi Hossein, Rahmim Arman, Zaidi Habib

Abstract excerpt

OBJECTIVE: To investigate the impact of harmonization on the performance of CT, PET, and fused PET/CT radiomic features toward the prediction of mutations status, for epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene (KRAS) genes in non-small cell lung cancer (NSCLC) patients. METHODS: Radiomic features were extracted from tumors delineated on CT, PET, and wavelet fused PET/CT images...

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PMID: 35051856
DOI: 10.1016/j.compbiomed.2022.105230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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