Back to search

Article

Assessing bactericidal dynamics of persister-manifested clinical isolates in the presence of macrophages and antibiotics

2025-12-25

Abstract excerpt

<h4>ABSTRACT</h4> Antibiotics are often depicted to reduce bacterial load for immuno-clearance. Recurring infections can be caused by bacteria persisters that survived antibiotic treatment. It is unclear how the host immunity manages infection by persister-manifested strains during antibiotic treatment. Differentiated THP-1 macrophages were exposed to persister-manifested clinical isolates at various multipliciti...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
2b68bb51-443c-5221-bc20-bc10ef8e91ab
DOI
10.64898/2025.12.22.696100
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Assessing bactericidal dynamics of persister-manifested clinical isolates in the presence of macrophages and antibioticsDOI 10.64898/2025.12.22.696100
Fighting bacterial persistence: Current and emerging anti-persister strategies and therapeutics.Semantic proximity
Isolation and characterization of persisters of the pathogenic microorganism <i>Staphylococcus aureus</i>Semantic proximity
The Persister Character of Clinical Isolates of Staphylococcus aureus Contributes to Faster Evolution to Resistance and Higher Survival in THP-1 Monocytes: A Study With MoxifloxacinSemantic proximity
Persistence phenotype of adherent-invasive <i>Escherichia coli</i> in response to ciprofloxacin, revealing high-persistence strainsSemantic proximity
Role of persister cells in chronic infections: clinical relevance and perspectives on anti-persister therapiesSemantic proximity
The Pharmacology of Bacterial Persistence: From Antibiotic Tolerance to Antimicrobial ResistanceSemantic proximity
Antibiotic-tolerant persisters are pervasive among clinical <i>Streptococcus pneumoniae</i> isolates and show strong condition-dependenceSemantic proximity
Persistent bacterial infections, antibiotic tolerance, and the oxidative stress responseSemantic proximity
Clinical isolates of <i>Enterobacter</i> species can persist in human macrophages without bacterial replication and minimal cellular cytotoxicitySemantic proximity
Strategies Used by Bacteria to Grow in MacrophagesSemantic proximity
Unravelling mechanisms of meropenem induced persistence facilitates identification of GRAS compounds with anti-persister activity against <i>Acinetobacter baumannii</i>Semantic proximity
Isolation and characterization of persisters of the pathogenic microorganism Staphylococcus aureusSemantic proximity
Select a neighboring publication to make it the new centre.