Article

CRABP2 Upregulation in Perichondral Stem Cells is Associated with Microtia

2025-12-27

Abstract excerpt

Microtia is a common congenital craniofacial malformation characterized by the partial or complete absence of the external ear structure. Despite its relatively high incidence, the pathogenesis of microtia remain poorly understood. In this study, we analyzed both single-cell and bulk RNA sequencing data from microtia cases and identified a population of COL1 + HES1 + mesenchymal stem cell in perichondrium with s...

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Literature Corpus work: 2b2bae79-abc7-5526-8006-2c40ab718c63
DOI: 10.64898/2025.12.18.25342452

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