Article

Pathway-Level Integration of Proteogenomic Data in Breast Cancer Using Independent Component Analysis

2017-08-13

Abstract excerpt

<h4>ABSTRACT</h4> Recent advances in the multi-omics characterization necessitate pathway-level abstraction and knowledge integration across different data types. In this study, we apply independent component analysis (ICA) to human breast cancer proteogenomics data to retrieve mechanistic information. We show that as an unsupervised feature extraction method, ICA was able to construct signatures with known biolo...

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Literature Corpus work: 2ad87016-9268-5a79-a82e-f7566f191930
DOI: 10.1101/175687

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