Article
Exploring the Mechanism of Tetramethylpyrazine in the Treatment of Osteoarthritis Based on Network Pharmacology
2023-09-01
Abstract excerpt
<h4>Background: </h4> Osteoarthritis(OA) is the most common joint disease, mainly damaging the articular cartilage and involving the whole joint tissue. It has the characteristics of a long course, repeated symptoms, and a high disability rate, and the incidence trend is gradually increasing. Tetramethylpyrazine(TMP) is the primary alkaloid active substance in Ligusticum wallichii, a traditional Chinese medicine,...
Topics
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- Bioinformatics and Genomic Networks
- Computational Drug Discovery Methods
- Flavonoids in Medical Research
- Gout, Hyperuricemia, Uric Acid
- Inflammatory mediators and NSAID effects
- Natural product bioactivities and synthesis
- Pharmacological Effects of Natural Compounds
- Rheumatoid Arthritis Research and Therapies
Identifiers and source
- Literature Corpus work
- a1e03ede-dd44-5cb8-bdc5-291f8bcad383
- DOI
- 10.21203/rs.3.rs-3307865/v1
