Article

Microbiome-TP53 Gene Interaction in Human Lung Cancer

2018-02-28

Abstract excerpt

<h4>Background</h4> Lung cancer is the leading cancer diagnosis worldwide and the number one cause of cancer deaths. Exposure to cigarette smoke, the primary risk factor in lung cancer, reduces epithelial barrier integrity and increases susceptibility to infections. Herein, we hypothesized that somatic mutations together with cigarette smoke generate a dysbiotic microbiota that is associated with lung carcinogene...

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Literature Corpus work: 2a8a6f9a-1beb-5b36-83a4-068de6e184d9
DOI: 10.1101/273524

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