Article

Label-free microscopy enables high-throughput identification of genes controlling biofilm development

2025-09-03

Abstract excerpt

The biofilm mode of growth plays a critical role in microbial ecology and in the persistence of human pathogens. Yet, much remains unknown regarding the molecular determinants of biofilms in human pathogens. In this study, we present label-free analysis of biofilms (LFAB), an imaging approach that combines time-lapse, low-magnification brightfield microscopy with regional optical density measurements to quantify b...

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Literature Corpus work: 2a80f507-bb1b-5eea-81b3-3c326b08d939
DOI: 10.1101/2025.09.02.673883

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