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Personalized neoadjuvant strategy using 70-gene assay in ER-positive/HER2- negative breast cancer to increase breast-conserving surgery rate (KBCSG016: PLATO trial)

2025-05-05

Abstract excerpt

<title>Abstract</title> <p>We investigated whether tailored neoadjuvant therapy (chemotherapy [NCT] or endocrine therapy [NET]) guided by a 70-gene assay could improve breast-conserving surgery (BCS) rates among patients with ER-positive/HER2-negative breast cancer initially deemed ineligible for BCS. Of 130 prospectively enrolled patients (stage II–IIIA, across four Korean centers), 92 were analyzed. Patients cl...

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Literature Corpus work: 2a3e1718-8743-5cd1-a0cd-b1a864a03039
DOI: 10.21203/rs.3.rs-6287262/v1

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